African Journal of Poultry Farming ISSN 2375-0863 Vol. 5 (3), pp. 177-184, March, 2017. © International Scholars Journals
Full Length Research Paper
Safety and efficacy studies of Newcastle Disease vaccines in very young African local ecotypechicks and in commercial pullets
1Domingue G*, 1Peters, A 2Muhairwa AP, 2Chiwanga GH, 2Msoffe PL, 3Jaglarz A, 4Wachira J, 4Musau AM, 4Kyangu NK and 1Thevasagayam S
1GALVmed (Global Alliance for Veterinary Medicines), Doherty Building, Pentlands Science Park, Edinburgh.EH26 0PZ, Scotland,
2SUA (Sokoine University of Agriculture), Department of Veterinary Medicine and Public Health, Faculty of Veterinary Medicine, Sokoine, P.O. Box 3021, Chuo KikuuMorogoro, Tanzania,
3MRI (Moredun Research Institute), Pentlands Science Park, Edinburgh, EH26 0PZ. Scotland, 4KEVEVAPI (Kenya Veterinary Vaccine Production Institute), Vaccine Production Building, Veterinary Investigation Labs, Nairobi, Kenya.
Received 31 October, 2016; Revised 04 December, 2016; Accepted 13 December, 2016 and Published 14 March, 2017
Two Good Clinical Practice studies are described. Firstly, thesafety and efficacyof live, attenuated LaSota and l-2 Newcastle Disease (ND) vaccines and inactivated, adjuvanted ITA-NEW ND vaccine were evaluated in eight-day old local ecotype chicks.For all vaccines safety and efficacyweresatisfactory and serological titres exceeded the putative protective level of >23before14 days post-vaccination. The vaccinated groups displayed no significant differences.
Keywords: Newcastle Disease vaccines, agricultural development, thermotolerance, LaSota, I-2, ITA-NEW, Clone 30.