International Journal of Public Health and Epidemiology

International Journal of Public Health and Epidemiology ISSN: 2326-7291 Vol. 6 (6), pp. 373-382, June, 2017. © International Scholars Journals

Full Length Research Paper

Race-and sex-related differences in the incidence of coronary heart disease in the First National Health and Nutrition Examination Survey Epidemiologic Follow-Up Study

1,2Rodrigue Pierre*, 1C Perry Brown,1Charlotte Baker,1Matthew Dutton,2Oghenekome Onokpise, 3Brian Hickey

1Institute of Public Health, Florida Agricultural and Mechanical University 1601 S Martin Luther King Jr Blvd, Tallahassee, FL 32307, USA, Tallahassee, Florida, 2College of Agriculture and Food Science, Florida Agricultural and Mechanical University, Tallahassee, Florida, 3Department of Health, Physical Education and Recreation, Florida Agricultural and Mechanical University, Tallahassee, Florida.

Corresponding author. E-mail: nealpier@yahoo.com

Accepted 09 May, 2017

Abstract

Despite the many cardiovascular studies conducted in the United States (US), nationally representative estimates of incidence of coronary heart disease (CHD) have been lacking. This study aimed at investigating incidence estimates of CHD in a nationally representative sample of the US population and to compare race- and sex-related incidence estimates. We used data from the First National Health and Nutrition Examination Survey Epidemiologic Follow-Up Study (NHEFS) [n = 6,346]. We determined cumulative incidence and incidence density and used log-rank and chi-square test for estimates comparison. A total of 382 CHD events occurred among 6,346 study participants from 1971 to 1992. The cumulative incidence was 9.93% in the NHEFS cohort; 13.46% among men and 7.00% among women (P< .001); 9.72% among Whites and 11.01% among non-Whites (P = .64). The incidence density, per 1,000 person-years, was 3.68 in the NHEFS cohort; 4.99 among men and 2.66 among women (P< .001); 3.65 among Whites and 3.90 among non-Whites (P = .67). From 1971 to 1992 in the US, the cumulative incidence of CHD was 9.93% and the incidence density was 3.68 per 1,000 person-years. While CHD incidence did not vary across race, males had a higher incidence than females.   

Keywords: Cumulative incidence, incidence density, coronary heart disease, sex-related differences, race-related differences, Kaplan Meier, National Health and Nutrition Examination Survey Epidemiologic Follow-Up Study.